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Afrezza

Afrezza from Mannkind

Afrezza (insulin human) Inhalation Powder is the only ultra rapid-acting inhaled insulin indicated to improve glycemic management in people with diabetes ages 6 and older. Available by prescription only. 

For complete information, visit the Afrezza website.

Afrezza insulin inhaler held between an index finger & thumb to show size
Afrezza insulin inhaler with doses of 4, 8 & 12 units

Device Type:

Inhalable Insulin

Reusable Disposable:

Disposable (Single dose only)

Medicine Type:

Afrezza is an ultra rapid-acting inhaled insulin taken at mealtime and helps manage postprandial plasma glucose (PPG) in people with diabetes ages 6 and older.

Insulin Type:

Rapid Acting

Dose Delivery:

Dose is inhaled via single use cartridges.

Largest Dose Possible:

Available in 4-unit, 8-unit and 12-unit single-dose cartridges of insulin powder. For Afrezza doses exceeding 12 units, patients may use a combination of existing cartridge strengths.

Total Capacity:

Available in 4-unit, 8-unit and 12-unit single-dose cartridges of insulin powder. For Afrezza doses exceeding 12 units, patients may use a combination of existing cartridge strengths.

Memory Function:

No

Audible Click:

Yes

Assistive Dexterity Issue Options:

Yes

Patient Resources

HCP Resources

Training Resources: 


ADCES Resources

Manufacturer Programs

Other Programs

  • Available by prescription, Afrezza® (insulin human) Inhalation Powder is the only available ultra rapid-acting inhaled insulin indicated to improve glycemic control in patients with diabetes ages 6 years and older.
  • Afrezza consists of a dry powder formulation of human insulin delivered from a small and portable inhaler.
  • Afrezza is administered at the beginning of the meal. After inhalation, the insulin passes quickly through the lungs and into the bloodstream (<1 minute). This rapid absorption allows Afrezza to begin reducing blood sugar levels within about 12 minutes of administration.
  • Afrezza can cause serious side effects including sudden lung problems (bronchospasms). Patients with long-term (chronic) lung problems such as asthma or chronic obstructive pulmonary disease (COPD) should not use Afrezza. Afrezza is not for use to treat diabetic ketoacidosis.
  • Afrezza is not for use in patients who smoke or have recently stopped smoking (less than 6 months).
  • Afrezza must be used with long-acting insulin in people who have type 1 diabetes. For more information and full Prescribing Information go to www.afrezza.com.

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January 2026

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DISCLAIMERS: 

This site and its services do not constitute the practice of medical advice, diagnosis or treatment. Always talk to your diabetes care and education specialist or health care provider for diagnosis and treatment, including your specific medical needs. If you have or suspect that you have a medical problem or condition, please contact a qualified health care professional immediately. To find a diabetes care and education specialist near you, visit the ADCES finder tool.

ADCES and danatech curate product specifics and periodically review them for accuracy and relevance. As a result, the information may or may not be the most recent. We recommend visiting the manufacturer's website for the latest details if you have any questions.

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